Kettapeptin: Isolation, Structure Elucidation and Activity of a New Hexadepsipeptide Antibiotic from a Terrestrial Streptomyces sp.
نویسندگان
چکیده
منابع مشابه
Seitomycin: isolation, structure elucidation and biological activity of a new angucycline antibiotic from a terrestrial Streptomycete.
A new antibiotic, named seitomycin (1c), and the known microbial metabolite tetrangulol methyl ether (2) were found in the ethyl acetate extract of two terrestrial Streptomyces sp. isolates. The structure of the new antibiotic was elucidated by spectroscopic studies and by comparison of the NMR data with the structurally related hatomarubigin C (1a) and SM-196 B (1b). Seitomycin (1c) showed mod...
متن کاملIsolation and structure elucidation of a new alkaloid from the Indonesian Blue-Green Alga Arthrospira platensis
A new alkaloid (1) and two known compounds (2 and 3) were isolated from the blue-greenalga Arthrospira platensis. Their structures were determined on the basis of spectroscopic data.According to the obtained data and values in the literature, the compounds were concluded to beeckol.
متن کاملL-156,602, a C5a antagonist with a novel cyclic hexadepsipeptide structure from Streptomyces sp. MA6348. Fermentation, isolation and structure determination.
The recently discovered class of cyclic hexadepsipeptide antibiotics is exemplified by azinothricin1) and A83586C2). In our search for novel substances with C5a antagonistic properties, a member of this class, L-156,602, was isolated from a newly isolated strain of streptomycete and found to be a competitive inhibitor of the binding of the anaphylatoxin C5a to its receptor on human PMNs3). Beca...
متن کاملisolation and identification of a new cold and alkaline tolerant antibiotic producing streptomyces sp. from soil
conclusions the crude extract of streptomyces sp. acs52 had high antibacterial activity against a wide spectrum of bacteria and could be of interest due to its features such as ability to grow at low temperatures and alkaline ph levels. results streptomyces sp. acs52 is a cold-resistant alkalophilic bacterium strain with antibacterial activity against a broad spectrum of pathogenic bacteria. th...
متن کاملChinikomycins A and B: isolation, structure elucidation, and biological activity of novel antibiotics from a marine Streptomyces sp. isolate M045.
In our screening of marine Streptomycetes for bioactive principles, two novel antitumor antibiotics designated as chinikomycins A (2a) and B (2b) were isolated together with manumycin A (1), and their structures were elucidated by a detailed interpretation of their spectra. Chinikomycins A (2a) and B (2b) are chlorine-containing aromatized manumycin derivatives of the type 64-pABA-2 with an unu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 2006
ISSN: 0021-8820,1881-1469
DOI: 10.1038/ja.2006.44